A robust, decades-deep evidence base for whole-person recovery
In a variety of randomized and non-randomized trials, MISSION has been shown to be successful for a myriad of populations — including criminal justice-involved veterans, female offenders returning to the community, and veteran and non-veteran clients who have experienced homelessness.

Better outcomes across the domains that matter most
Previous studies examining the efficacy of the MISSION approach have shown improved outcomes across the areas that most affect a person's ability to recover and stay in the community:
MISSION's efficacy has been documented for criminal justice-involved veterans, female offenders returning to the community, and veteran and non-veteran clients who have experienced homelessness.
Recognized by the National Institutes of Health
"A Whole Health Approach for Treating Opioid Addiction and Mental Illness — seeking sustainable models of integrated care."
The way we identify and treat mental health, substance use, and pain remains fragmented, even though these conditions have always been intimately connected. Effective treatment often combines several components: medications, peer support, group therapy, and links to community services such as food banks, housing services, employment counseling, and educational training.
Because this type of care can be difficult to access, scientists funded by the NIH Helping to End Addiction Long-term® (HEAL) Initiative are optimizing it by breaking the treatment into parts and testing different combinations that may be effective and could be covered by insurance.

A model trusted at the national level
MISSION's evidence base has earned recognition and funding from the country's leading health and justice agencies.
SAMHSA NREPP listing
MISSION-Vet is included in the Substance Abuse and Mental Health Services Administration (SAMHSA) National Registry of Evidence-based Programs and Practices (NREPP) to address co-occurring disorders among homeless individuals.
NIH · VA · CDC-funded research
The MISSION model is backed by research funding from the National Institutes of Health, the Department of Veterans Affairs, and the Centers for Disease Control and Prevention.
Adopted into national & state plans
Deployed within the Veterans Health Administration as part of the national plan to end veteran homelessness, utilized in a Massachusetts statewide plan to end homelessness, and written into public law for delivery alongside veteran treatment courts in Massachusetts.
Listed in the PEW Results First Clearinghouse Database
MISSION is listed in The Pew Charitable Trusts' Results First Clearinghouse Database, which aggregates program ratings from leading national registries, including SAMHSA's NREPP. Enter "MISSION" into the search box to see the full listing.
Published work on MISSION treatment outcomes
A selection from the chronological list of peer-reviewed studies on MISSION treatment outcomes and related findings, spanning 2005 to 2023. Each links to the published article.