Research that moves whole-person care forward.
The MISSION Behavioral Health Lab is dedicated to conducting state-of-the-art research toward advancing our understanding of the etiology, consequences, and treatment of addiction and mental health, as well as the implementation of evidence-based practices. The Lab serves as an academic incubator for collaborations within the Department of Medicine, the UMass Chan Medical School, other University of Massachusetts campuses, and beyond.

Current MISSION research & implementation
Federally and state-funded studies testing and delivering MISSION wraparound services for individuals with co-occurring substance use and mental health disorders.
MISSION-STAR-COD
Supporting Treatment and Recovery for Co-Occurring Disorders. Augments Medication for Opioid Use Disorder (MOUD) usual care with the time-limited MISSION wraparound intervention for individuals with co-occurring opioid addiction and mental illness. A 4-year, 5-arm RCT with a fractional factorial design among 1,000 patients across 9 MOUD programs, testing the added benefit of MISSION or its components plus MOUD compared to MOUD alone.
PI: David Smelson, Psy.D. · Supported by NIH/NIMH · 2021–2026
MISSION-STAR-LS
Supporting Treatment Access and Recovery through Linkage and Support. A randomized controlled trial embedded within the City of Worcester 911 call center that compares MISSION and low-intensity linkage support.
PI: David Smelson, Psy.D. · Supported by CDC · 2021–2025
MISSION-OUD
Supporting Treatment Access and Recovery for Opioid Use Disorder. Provides wraparound MISSION services to individuals with co-occurring disorders to increase access to mental health, substance use, trauma, and employment services.
PI: Jennifer Harter, Ph.D. · Supported by SAMHSA · 2021–2027
MISSION-Springfield
Enhances existing COD treatment services provided through the Springfield Drug Court by administering MISSION-Criminal Justice services — intensive case management, peer support, COD and trauma-informed counseling, and care linkage and coordination to recovery and wraparound supports, including Medications for opioid use disorder (MOUD), employment, and housing.
PI: Sheila Casey, Esq. · Supported by SAMHSA/CSAT · 2020–2025
Serving Veterans through the VA
Implementation science and clinical trials advancing MISSION for Veterans experiencing homelessness, opioid dependence, and reentry from incarceration.
Partnering across the field
Collaborative studies extending MISSION's reach into whole health coaching and gender-specific treatment.
A legacy of MISSION research
Previous MISSION projects have focused on the development, implementation, and evaluation of the co-occurring substance use and mental health disorders (CODs) services provided through MISSION programs. These studies were the result of collaborative efforts between multiple partner organizations. Inactive MISSION project abstracts are listed below in roughly chronological order.